What is Qwo ?
Qwo (collagenase clostridium histolyticum-aaes, Endo Aesthetics) is the first FDA-approved drug device for cellulite treatment in women. It is a solution of liquid collagenase, an enzyme that breaks down and remodels collagen, a key protein in fibrous bands that creates cellulite dimples. Qwo is a series of 3 injection treatments spaced 3 weeks apart. It is hard to believe that 90% of women have cellulite.
How it Works?
The primary contributing factor to cellulite is the fibrous connective tissue called the fibrous septae. When the skin (3) thins with aging, and the fat cells (2) enlarge and push against the skin, the fibrous septae (1) bands thicken and push against the skin to create dimples. This causes the visible cellulite on the buttocks.
QWO is made from enzymes called collagenases. These enzymes are thought to target the structural causes under the skin, where cellulite starts, to release the fibrous bands, redistribute fat cells, and stimulate the growth of new collagen. Qwo will be injected three times into the fibrous septae to slowly release the fibrous strands.
Why is this specifically for cellulite in women?
A primary factor in the cause of cellulite is the collagen containing septae which attach the skin to the underlying fascia layers. The septae tether the skin which, with additional contributing protrusions of subcutaneous fat, causes the surface dimpling characteristic of cellulite. These fibrous septae are oriented differently with varying thickness in females than in males. QWO™ is tested and FDA-cleared specifically for cellulite in adult women.
